Researchers published in the journal Nature analyzed the gut-brain connection in mice and found that there is evidence of sympathetic nervous system activation outside of the gut and that it is controlled by microbiota via a gut-brain circuit.

We know that connections exist between the gut and the brain. Previous studies have also shown that these connections regulate physiologic intestinal functions like nutrient absorption and motility, as well as brain-led feeding behavior. Until now, the theory behind the relationship has been explained by circuits that detect gut microorganisms and relay the information to the central nervous system so they can regulate gut physiology.